Nothing to do with hardware video alpha, it's the colour calibration settings profile that basically makes sure that the colours, brightness, gamma, contrast appear correctly on that monitor.
Any visual input or output device, such as monitors, printers and scanners should be calibrated so that the images appear the same on each device and on other peoples' equipment.
The monitor should come with it's own calibration software and Adobe ships its own with its software "Adobe Gamma" I think. Run the saftware and follow its instructions.