> How do I create more than one site using CMSMS on local server?
Maybe there is an even better system, but what I'm typically doing is to install CMS Made Simple in a new sub-directory under my web-root, but point it to a fresh database in MySQL.
Example, create databases cms_client1 and cms_client2 and then the directories /var/www/html/client1 and /var/www/html/client2 (this assumes an Apache on RedHat host). Install CMSms in both directories. The two admin interfaces can then be found at http://localhost/client1/admin/ and the same for client2.